MT-45 (IC-6) is an opioid analgesic drug. It is chemically a 1-substituted-4-(1,2-diphenylethyl)piperazine derivative, which is structurally unrelated to
most other opioid drugs. Racemic MT-45 has around 80% the potency of morphine, with almost all opioid activity residing in the (S) enantiomer (the
opposite stereochemistry from the related drug lefetamine). It has been used as a lead compound from which a large family of potent opioid drugshave
been developed, including full agonists, partial agonists, and antagonists at the three main opioid receptor subtypes.Fluorinated derivatives of MT-45
such as 2F-MT-45 are significantly more potent as p-opioid receptor agonists, and one of its main metabolites 1,2-diphenylethy piperazine also
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Habit-forming
These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.
Depressant
Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.
Opioid
Opioids are pain-killing depressants which may also cause euphoria.
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